Experimental Study of <i>Emilia Sonchifolia</i> Combined with <i>Coptidis Rhizoma</i> for the Prevention and Treatment of Oral Ulcer

Objective: This paper aims to investigate the therapeutic effect of combination Emilia Sonchifolia and Coptidis Rhizoma on oral ulcer rats. Methods: 36 SD rats half male female were kept for 7 days, 6 among them selected as normal group by random sampling method, rest randomly divided into model group, positive control combined after establishment model. The given blank film, was Guilin Watermelon Frost, corresponding which administered days continuously, 2 times per day. healing assessed at end last day administration, area calculated 1st, 3rd, 5th 7th successful modeling, serum levels IL-2 TNF-α in detected Sonchifolia. Results: grading better than other groups, difference statistically significant when compared with (p smaller that all effective reducing ulcer, more effective. level pro-inflammatory factor reduced anti-inflammatory increased is treatment rats, drug alone.